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In vitro inhibitor effect and molecular docking of thiamine (vitamin B 1), riboflavin (vitamin B 2), and reference inhibitor captopril on angiotensin-converting enzyme purified from sheep plasma

Ciftci MH, Turkoglu V, Bas Z, Celikezen FC 2024 Archives of physiology and biochemistry

Abstract

Objective Angiotensin-converting enzyme (ACE, EC 3.4.15.1) is a very important factor in the regulation of blood pressure. Also, the inhibition of ACE with natural compounds has been a very important research area in the treatment of high blood pressure. ACE was purified and characterized from sheep plasma. Molecular…

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Studied ingredients

Species involved

Sheep

Keywords

PurificationInhibitionangiotensin-converting enzymeThiamineriboflavin

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