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Study

Safety and efficacy of a feed additive consisting of 4-hydroxy-2,5-dimethylfuran-3(2H)-one for all animal species other than dogs and cats (ADISSEO France SAS, ADM International Sàrl, Laboratoires Phodé S.A.S., LUCTA S.A., Norel, S.A.)

Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M 2025 EFSA Journal

Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the authorisation of a feed additive consisting of 4-hydroxy-2,5-dimethylfuran-3(2H)-one for all animal species other than dogs and cats. 4-Hydroxy-2,5-dimethylfuran-3(2H)-one is currently authorised for use as a sensory additive (functional group: flavouring compounds) for cats and dogs at a recommended maximum content of 18 and 25 mg/kg complete feed, respectively. The FEEDAP Panel concludes that the use of the additive 4-hydroxy-2,5-dimethylfuran-3(2H)-one at the maximum use level proposed by the applicants (10 mg/kg complete feed) is safe for all animal species other than cats and dogs. 4-Hydroxy-2,5-dimethylfuran-3(2H)-one is safe for consumer and environment, however, it is irritant to skin, eyes and is a dermal and respiratory sensitiser. It should be considered irritant to the respiratory tract. Any exposure is considered a risk. 4-Hydroxy-2,5-dimethylfuran-3(2H)-one is used in food as a flavouring and its function in feed is essentially the same as that in food. Moreover, the Panel notes that the additive is already authorised in feed for cats and dogs. Therefore, no further demonstration of efficacy is necessary.

Studied ingredients

Species involved

DogsCats

Keywords

SafetyFlavouringsSensory AdditivesAll Animal Species4‐Hydroxy‐2,5‐dimethylfuran‐3(2h)‐one

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