Description
What it is. Additive combining three viable bacterial strains: Bacillus subtilis FERM BP-07462, Enterococcus lactis FERM BP-10867 and Clostridium butyricum FERM BP-10866, produced as a solid preparation with a minimum content of 12 × 10^8 CFU/g of additive, in a 1:10:1 ratio.
What it is for. It belongs to functional group 4b, intestinal flora stabilisers, and is authorised for all poultry species for fattening, reared for laying, reared for breeding, and for ornamental birds. It may be used in drinking water and in combination with diclazuril, decoquinate or halofuginone, within their respective authorisation conditions. An EFSA-reviewed study (BIO-THREE®) illustrates its use in broiler chickens as a complement to the dossier, without setting a usage level.
Points to watch. The instructions for use of the additive and premixtures must specify storage conditions and stability to heat treatment. Minimum content levels differ by production stage (fattening/laying: 2.4 × 10^8; breeding: 1.2 × 10^8). Operators must establish operating procedures and, where risks cannot otherwise be controlled, require personal protective equipment (respiratory and skin protection) during handling.
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