Preparation of endo-1,4-betaglucanase / EC 3.2.1.4, endo-1,3(4)-betaglucanase / EC 3.2.1.6 and endo-1,4-betaxylanase / EC 3.2.1.8

What it is. This is a multi-enzyme preparation combining endo-1,4-betaglucanase (EC 3.2.1.4), endo-1,3(4)-betaglucanase (EC 3.2.1.6) and endo-1,4-betaxylanase (EC 3.2.1.8). It is a feed additive produced by fermentation, intended to break down non-starch polysaccharides (beta-glucans and arabinoxylans) present in cereal-based diets.

What it is for. This type of enzyme combination is generally used to improve the digestibility of cereal-based diets by reducing the viscosity caused by beta-glucans and xylans in the digestive tract. It is generally used in poultry, and the EU register specifically lists ducks among the authorised species. It would generally be employed in compound feed formulation at the feed-manufacturing stage, where cereals such as barley, wheat or rye are significant dietary components.

Points to watch. The EU authorisation for this preparation in the listed species runs until 8 January 2028, after which status may be reviewed. No maximum inclusion level or dosage figure is provided in the available sources, so no quantitative limit can be stated here; formulators should refer to the specific authorisation conditions for exact use levels. As with other enzyme additives, activity and stability may vary depending on feed processing conditions and storage.